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Hydroxypropyl Betadex CAS 128446-35-5

  • Brand:

    AECOCHEM
  • CAS NO.:

    128446-35-5
  • Product Name:

    Hydroxypropyl Betadex
  • Synonyms:

    Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrin 2-hydroxypropyl ethers; HPBCD; HPCD
  • Molecular Formula:

    C42.(H)70-n.O35.(C3H7)n
  • MW:

    1541.54
  • Packaging:

    20kg/drum
Product Detail

Welcome to buy Hydroxypropyl Betadex CAS 128446-35-5 from AECOCHEM,which would be your reliable partner in China.AECOCHEM is a professional chemicals supplier.If you are interested in Hydroxypropyl Betadex or want to purchase from China, please send E-mail to sales@aecochemical.com.

 

Identification:

Product Name:Hydroxypropyl Betadex

CAS :128446-35-5

Synonyms :Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrin 2-hydroxypropyl ethers; HPBCD; HPCD

Molecular Formula :C42.(H)70-n.O35.(C3H7)n

Molecular Weight :1541.54

EINECS :420-920-1

 

Properties

Melting point:278 °C (dec.)

Refractive index:125 ° (C=1, H2O)

Storage temp.:”2-8°C

Solubility:H2O: 45 % (w/v)

Form:Solution (clear, colorless)

Color:White to slightly yellow

Optical activity:[α]26/D +139°, c = 1 in H2O

Water solubility:Soluble in water

 

Specification:

Appearance:White powder, insipid, innocent

Degree of Substitution:2.8-10.5

Clarity of solution:50%(w/v) water solution is clear

Identification(IR): same absorption bands with USP Hydroxypropyl Betadex RS

Loss on Drying:≤10

Conductivity:10%(w/v) water solution ≤200µS/cm

Propylene oxide:≤1ppm

Propylene glycol:≤2.5

Sum of Other Impurities:≤1

Betadex:≤1.5%

Residue on Ignition:≤0.2

Heavy Metal:≤20ppm

Chloride:≤0.05%

TAMC(cfu/g):≤1000 cfu/g

TYMC(cfu/g):≤100 cfu/g

Salmonella/E. Coli (cfu/g):Absent

 

Product Package: 

20kg/fiber drum,or according to the requirements of the customers.

 

Product Storage: 

Put in a sealed, dry and ventilated place, Guard Against Fire.

 

Application:

Hydroxypropyl-β-cyclodextrin (HP-β-CD) is the hydroxyalkylated derivatives of β- cyclodextrin (β-CD). HP-β-CD is non-toxic and has no side effect, and it can significantly improve the solubility of insoluble drugs to dissolve insoluble or poorly water-soluble drugs due to its structural particularity. Therefore, it can effectively increase bioavailability of drugs; it can also improve drug quality and variety of dosage forms, thereby being applied in development and production of new drugs. Globally, in-depth studies of the properties, preparation technology, stability, pharmacology, toxicology, teratogenic, mutagenic, carcinogenic, hemolysis, irritation and other aspects of HP-β-CD have already been performed; the safety of this drug has been evaluated accurately. Among all the derivatives of β-CD, HP-β-CD is considered as a type of pharmaceutical excipients with most complete research data and highest medicinal value, and it has been studied in-width and in-depth mostly.

 

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